Anti-TCEB1 Polyclonal Antibody

商品货号：	商品品牌：	规格	基本售价：	选择规格
K002592P-50ul	solarbio	50ul	960.00元
K002592P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-TCEB1 Polyclonal Antibody
别名	ELOC;TCEB1;SIII;
应用	WB
稀释比例	WB 1:500-2000.
交叉反应	Human Mouse Rat
蛋白分子量	12kDa
Gene ID	6921
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human TCEB1
性状	液体
Public Immunogen Range	Recombinant protein of human TCEB1
Subcellular Locations	Nucleus
Swiss Prot	Q15369
克隆类型	Polyclonal Antibody
背景资料	This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified.