CDKN2B polyclonal antibody (A01)
产品名称: CDKN2B polyclonal antibody (A01)
英文名称: CDKN2B polyclonal antibody (A01)
产品编号: H00001030-A01
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length recombinant CDKN2B.
- Immunogen:
- CDKN2B (AAH14469, 1 a.a. ~ 138 a.a) full-length recombinant protein with GST tag.
- Sequence:
- MREENKGIPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEERGHRDVAGYLRTATGD
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- 50 % glycerol
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (41.29 KDa) .
- MSDS:
Download
- Application Image
- Western Blot (Recombinant protein)
- ELISA
- Entrez GeneID:
- 1030
- GeneBank Accession#:
- BC014469
- Protein Accession#:
- AAH14469
- Gene Name:
- CDKN2B
- Gene Alias:
- CDK4I,INK4B,MTS2,P15,TP15,p15INK4b
- Gene Description:
- cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
- Omim ID:
- 600431
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq
- Other Designations:
- CDK inhibitory protein,CDK4B inhibitor,OTTHUMP00000021154,OTTHUMP00000021155,cyclin-dependent kinase 4 inhibitor B,cyclin-dependent kinase inhibitor 2B,cyclin-dependent kinases 4 and 6 binding protein,multiple tumor suppressor 2,p14_CDK inhibitor,p14_INK4
- Interactome
- Related Disease
- Adenocarcinoma
- Arthritis, Rheumatoid
- Asthma
- Ataxia telangiectasia
- Atherosclerosis
- Atherosclerosis
- Bipolar Disorder
- Birth Weight
- Brain Ischemia
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Calcinosis
- Carcinoma
- Carcinoma, Basal Cell
- Carcinoma, Medullary
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Chromosomal Instability